I enjoy reading the "What's in your bag?" thread. It gives me good ideas for what to bring. I've since adjusted what I carry with me during Gen Con. I've both added and taken away items.
I think it'd be interesting to have a thread on what you have brought in the past, but found unnecessary and hence don't bother bringing any more. While some here are "vets" and have it dialed in, I think this would help the newer attendees have a better idea for what should be left behind.
I'll start.
Rulebooks for my RPG's events: They were heavy (after carrying them the full day), and at the gaming table were rarely needed. Additionally, there are always people around who have them, especially the GM. Speaking of which...as a GM, try to only bring the necessary core book(s). If you can have the books electronically, then fine. Otherwise, I'd say try to make due without them.
Drinks/snacks like I was going to be out for 2-3 days: I wanted to make sure my daughter & I had enough to get us through the day. I always returned to the hotel with a few crushed granola bars and unopened bottles. Now, I bring one bar and piece of fruit for each of us and we carry one water bottle to refill at the con. There are plenty of places to eat and drink around the area, and I'd say it's a good idea to schedule a meal break during your day anyway.
Swag: I loved picking up swag, both from the goodie bag back in the day and from various vendors. It was exciting to get my hands on new/limited items/promos. However, I've learned that once I got back from the con and the dust settled, the random swag was not all that great. Promos for games you don't play and are not really interested in is just a waste of space. Don't bother with swag you don't really care about. Perhaps there's the aftermarket aspect, but cards for some obscure game that will fetch $1 on ebay are not really worth your precious Gen Con time/effort.
So, what item(s) have your carried before that you no longer bring or bother with?